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Reproductive Endocrinology and Infertility

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    Roche CFO flags need to bolster late-stage drug development

    Swiss drugmaker Roche needs to have better drug development projects in advanced stages to bolster its battered stock market value, its
    finance chief said on Thursday.

    "The point is really the setbacks we had last year in the late-stage pipeline... We have to now fill up the pipeline again and prove ourselves that we really have a strong late-stage pipeline," CFO Alan Hippe
    told a press conference.

    Roche: have abandoned some trials due to U.S.

    drug pricing plans

    Roche said it had abandoned certain drug development projects or acquisitions under
    consideration because of planned price cuts in best-selling prescription medicines
    in the United States. Speaking in a media call after the release of first-half results,
    CEO Thomas Schinecker said the Swiss group was not taking the lead on any legal action against the
    U.S.

    government project under the Inflation Reduction Act (IRA), because other large drugmakers were much more severely affected,
    but its work on new drugs was impacted still.

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    The factory that fills the self-injection pens for booming weight-loss drug
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    according to detailed FDA reports on the inspections, obtained by Reuters under freedom of information laws.


    Obesity drugs don't make WHO's essential list, but Ebola, MS drugs added

    Obesity drugs will not join the World Health
    Organization's (WHO) latest essential medicines list, but treatments for diseases, including Ebola and
    multiple sclerosis will, documents published by the U.N.


    agency showed. The WHO's essential medicines list is a catalog
    of the drugs that should be available in all functioning health systems.


    Exclusive-UK probes Novo's Ozempic, weight-loss drug Saxenda over suicidal,
    self-harming thoughts

    Britain is reviewing a class of drugs used in a diabetes medicine and a weight-loss treatment sold by Novo Nordisk after some patients reported suicidal or self-harming thoughts,
    two weeks after similar action by the European Union. The Medicines and Healthcare products Regulatory Agency (MHRA) said in a statement
    to Reuters late on Tuesday it was reviewing safety data on a class of drugs known as GLP-1 receptor agonists.


    Eli Lilly's obesity drug succeeds in two late-stage studies

    Eli Lilly said on Thursday its experimental obesity drug met the main goals in two late-stage studies,
    with the drug helping patients reduce 26.6% weight on average in one of the studies following intensive lifestyle changes.


    The company said both the late-stage studies also achieved all secondary goals.


    Bristol Myers sales fall, cuts 2023 forecast as drugs face competition

    Drugmaker Bristol Myers Squibb said on Thursday its second-quarter sales fell more than expected and cut its
    full-year forecast as two of its top drugs, blood cancer treatment Revlimid
    and blood thinner Eliquis, face generic competition. The
    company now expects 2023 revenue to fall by low single digit percentages, primarily due to lower-than-expected Revlimid sales.


    It previously forecast a roughly 2% increase
    in revenue for the year.

    Bangladesh fears record high death toll from dengue outbreak

    Dengue is spreading rapidly through densely populated
    Bangladesh this rainy season, raising fears that the mosquito-borne
    disease could result in a record number of deaths and infections for the second
    consecutive year.

    At least 201 people, more than half of them in the
    capital Dhaka, have died and more than 37,000 have become
    infected with the virus so far this year, according to official
    figures.

    Eye drug success mitigates Roche's earnings decline

    Roche said first-half core operating profit fell 14%
    as the Swiss drugs and diagnostics maker was hit by a sharp decline in sales of COVID-19 products but the strong launch of a
    new eye drug mitigated the decline.

    It said in a statement on Thursday that core
    operating profit came in at 10.9 billion Swiss francs ($12.68 billion), in line
    with analysts' expectations,

    HCA Healthcare raises 2023 profit view as surgical procedure volumes rebound

    Hospital operator HCA Healthcare Inc on Thursday raised its annual profit forecast, betting on a recovery in surgical procedure volumes.


    The volumes of medical procedures are trending upwards after the U.S.

    government ended the public health emergency status for COVID-19 in May.
    Patients, particularly older adults, have been returning to hospitals for procedures such
    as hip and knee replacements.

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